2,4-dichlorobenzyl alcohol, amylmetacresol.
Composition: Each lozenge contains: 2,4-Dichlorobenzyl Alcohol 1.2 mg; Amylmetacresol 0.6 mg.
Difflam AB Sore Throat lozenges Orange: Orange coloured, round, biconvex lozenges having orange flavour with sweet taste.
Difflam AB Sore Throat lozenges Lemon: Yellow coloured, round, biconvex lozenges having lemon flavour with sweet taste.
Difflam AB Sore Throat lozenges Blackcurrant: Violet coloured, round, biconvex lozenges having blackcurrant flavour with sweet taste.
Difflam AB Sore Throat lozenges Honey Lemon: Brownish yellow coloured, round, biconvex lozenges having honey lemon flavour with sweet taste.
Pharmacology: Pharmacodynamics: 2,4-Dichlorobenzyl Alcohol and Amylmetacresol are antiseptics and possess antibacterial (bactericidal and bacteriostatic), antifungal and antiviral properties as demonstrated in vitro. When the two active agents are combined, a synergistic antibacterial action is observed leading to a reduced combined dose.
In-vitro studies demonstrated killing effects against some sore throat causing organisms such as Streptococcus pyogenes, Staphylococcus aureus, Haemophilus influenza and Moraxella catarrhalis, at 1 minute contact time. An overall reduction in the oral bacterial load was also seen in one in-vivo study.
In-vitro antiviral action against enveloped viruses including influenza A virus, para-influenza virus, respiratory syncytial virus, cytomegalovirus and coronavirus has also been observed for both amylmetacresol and dichlorobenzyl alcohol as well as the combination of the two after 1-2 minutes' contact.
For the symptomatic relief of mouth and throat infections.
Adults and children (over 6 years old): One lozenge to be dissolved slowly in the mouth every 2-3 hours up to a maximum of 12 lozenges in 24 hours.
Overdosage should not present a problem other than gastrointestinal discomfort.
Treatment should be symptomatic.
Hypersensitivity to any of the ingredients.
Do not exceed the stated dose.
Not to be given to children under 6 years.
If symptoms persist, have not improved, or have worsened after 3 days, consult a doctor or healthcare professional.
Patients with rare hereditary problems of glucose-galactose malabsorption or sucrose-isomaltose insufficiency should not take this medicine.
Pregnancy: There are no or limited amount of data from the use of amylmetacresol and 2,4-Dichlorobenzyl Alcohol.
As with all medicines care should be taken when using this product in pregnancy and medical advice sought if necessary.
Breast-feeding: It is unknown whether 2,4-Dichlorobenzyl Alcohol, amylmetacresol or metabolites are excreted in human milk.
A risk to the newborns/infants cannot be excluded.
Hypersensitivity reactions, glossodynia, and oral discomfort.
No clinically significant interactions are known.
Store below 30°C, in a dry place.
R02AA03 - dichlorobenzyl alcohol ; Belongs to the class of antiseptics used in throat preparations.
Difflam AB Sore Throat Lozenges
(orange/lemon/blackcurrant/honey lemon flavour) 12's; (orange/lemon/blackcurrant/honey lemon flavour) 6's
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